Yes, as long as you want the benefits of the iPod rather that specific features of the iTunes application program itself.
The iPod is seen by Linux as a hot-mountable disk device just like w USB thumb drive. One thing that is a little unusual (and annoying) is that when you transfer music to it, the filename of the MP3 file isn't important to it - I think it looks at the descriptive tags inside the MP3 file itself.
A number of popular Linux GUI apps support the iPod.
An IDE is no substitute for an Intelligent Developer.