Creating index on all join columns may not lead you to best results. An index is most useful when data in index column has a higher number of distinct values. RDBMS creates unique index on PK constraints. While creating an index if index values are as many as table rows which means that every column data is unique then it is mostly likely that you will not get your query time boosted. An index is a smart way of accessing rows faster than full table scan.
Most database -I know MySQL and Oracle does- provides analyze tools for sql optimization, this tool shows how RDBMS is joining tables and accessing rows, either using an index or full table scan and how much it costs. This is a general perception not specific to Ms Sql Server, hope it helps.