Griffon supports native libraries from the core itself. This means you can place platform specific jars and native libraries following a convention and the framework will pick them up. Currently supported platforms are: windows, linux, macosx and solaris (all 32bit versions).
Well, considering it is based on the lessons learned by the Grails team and community (5 years) plus more than 10 years in Swing land combined by the Griffon team, yes :-)
Stay put for a future release (0.3) in the next week or so.